Game review: Tampa Bay Buccaneers 51, New Orleans Saints 27

Rattler was 22 of 40 for 243 yards with one touchdown and two interceptions, both in the second half. Running back Alvin Kamara had 13 carries for 40 yards and a 4-yard touchdown run, the 60th of his career. Rookie receiver Bub Means had his first reception, his first touchdown catch (10 yards in the second quarter) and five catches for 45 yards. The Saints used their fourth combination on offense with guard/center Lucas Patrick missing. Connor McGovern started in his place. The running game was a struggle, the longest run was a 16-yard scramble by Rattler, and pass protection became an issue in the second half.

Paulson Adebo, Johnathan Abram and Cameron Jordan had interceptions for the Saints, while linebacker Willie Gay got a sack. But it wasn't enough to stop Mayfield and the Bucs. The former No. 1 overall draft pick was 24 of 36 for 325 yards with four touchdown passes and the three interceptions. Sean Tucker had 14 carries for 136 yards while Bucky Irving added 81 yards on 14 carries. They each had a touchdown. It is the fifth time in franchise history that the Saints have given up 50 or more points. The 594 yards are the second-most yards given up by the Saints in franchise history.

The Bucs, playing for the first time in 10 days, practiced all week at Tulane to avoid the effects of Hurricane Milton, which hit the Tampa Bay area. The Saints, who took a short break this week after Monday night's game, have an even shorter week as they host the Denver Broncos on “Thursday Night Football” at Caesars Superdome. The Broncos (3-2) play the Los Angeles Chargers on Sunday at 3:05 p.m.